Breadcrumb
Glossary of Terms and Abbreviations - N
A / B / C / D / E / F / G / H / I / J / K / L / M / N / O / P / Q / R / S / T / U / V / W / X / Y
NGS:
Next-generation sequencing
Nonsense variant:
A single base pair alteration which result in a premature stop codon.
Nonsynonymous variant (ns):
A single base pair alteration which results in an altered amino acid.
Novel variant:
A DNA alteration which has not been previously reported in a public database.
Nucleotide:
The building blocks of RNA and DNA polymers which consist of a nitrogenous base (adenine (A), guanine (G), thymine (T), or cytosine (C) in DNA; adenine (A), guanine (G), uracil (U), or cytosine (C) in RNA), a phosphate molecule, and a sugar molecule (deoxyribose in DNA; ribose in RNA)
Null allele:
An allele which results in a lack of the gene’s normal function.