Our CAP-accredited Clinical Division developed the first comprehensive targeted capture panel for inherited kidney diseases in the country, KidneySeq™. Physicians and genetic counselors use KidneySeq™ as a valuable tool in the diagnosis and management of their patients. Our multidisciplinary team of nephrologists, geneticists, and genetic counselors expertly review each patient’s results, carefully correlating phenotype and genotype to provide meaningful results. We proudly stand behind a solve rate of 40%. 

KidneySeqTM is a test consisting of 6 targeted capture panels of over 330 genes causally related to over 120 renal diseases offered by the IIHG to physicians as a test in the diagnosis and management of patients. 

The APOL1 test is a genotyping test which detects variants that comprise the G1 (NM_001136540:c.1024A>G, p.Ser342Gly and NM_001136540:c.1152T>G, p.Ile384Met) and G2 (NM_001136540:c.1160_1165delATAATT) risk alleles. The APOL1 test can be ordered by a physician as a tool in the counseling, evaluation and management of their patients.

Other Testing Options at UIHC

The MORL Clinical Diagnostics Division is a not-for-profit academic laboratory that focuses on non-syndromic hearing loss and complement-mediated renal disease.

Our experienced, board-certified genetic counselors with University of Iowa Health Care will help you understand which genetic tests provide "clinically actionable" information – and help you understand which genetic variants are known to cause disease and how you may prevent a disease from occurring or alter its progression.


UI Diagnostic Laboratories (UIDL) affiliated with UI Health Care, is a national reference laboratory offering academic expertise in specialty anatomic pathology services, advanced molecular genetic testing, and rapid renal biopsy consults. We offer very competitive turnarounds. All pathologists are available for immediate consultation by phone or email.

The Rare Renal Disease Clinic and the Renal Genetics Clinic are among the world’s best in diagnosing and treating rare genetic kidney diseases in children and adults. In the United States, a rare disease is defined as a disease that affects fewer than 200,000 people in the country. There are at least 150 different disorders that are considered to be rare kidney diseases. This means that only a few thousand people in the United States may have one of these diseases, so specialized care providers may be hard to find.