Our CAP-accredited Clinical Division developed the first comprehensive targeted capture panel for inherited kidney diseases in the country, KidneySeq. Physicians and genetic counselors use KidneySeq as a valuable tool in the diagnosis and management of their patients. Our multidisciplinary team of nephrologists, geneticists, and genetic counselors expertly review each patient's results, carefully correlating phenotype and genotype to provide meaningful results. 

KidneySeq

Comprehensive Inherited Kidney Disease Panel

KidneySeqTM is a test consisting of over 330 genes causally related to over 120 renal diseases. This test is offered by the IIHG to physicians and genetic counselors in the diagnosis and management of their patients. 

APOL1 Genotyping Test

The APOL1 Genotyping Test detects variants that comprise the G1 (NM_001136540:c.1024A>G,p.Ser342Gly and NM_001136540:c.1152T>G, p.Ile384Met) and G2 (NM_001136540:c.1160_1165delATAATT) risk alleles; and the G2 protective allele (NM_003661.4: c.792C>A, p.Asn264Lys). This test can be ordered by a physician or genetic counselor as a tool in the counseling, evaluation and management of their patients.

Other Testing Options at UIHC

Molecular Otolaryngology and Renal Research Laboratories (MORL)

The MORL Clinical Diagnostics Division is a not-for-profit academic laboratory that focuses on non-syndromic hearing loss and complement-mediated renal disease.

Genetic Counseling at UIHC

Our experienced, board-certified genetic counselors with University of Iowa Health Care will help you understand which genetic tests provide "clinically actionable" information – and help you understand which genetic variants are known to cause disease and how you may prevent a disease from occurring or alter its progression.

https://uihc.org/services/genetic-counseling 

UI Diagnostic Laboratories

UI Diagnostic Laboratories (UIDL) affiliated with UI Health Care, is a national reference laboratory offering academic expertise in specialty anatomic pathology services, advanced molecular genetic testing, and rapid renal biopsy consults. We offer very competitive turnarounds. All pathologists are available for immediate consultation by phone or email.

UIHC Rare Kidney Disease and Genetics Clinics

The Rare Renal Disease Clinic and the Renal Genetics Clinic are among the world’s best in diagnosing and treating rare genetic kidney diseases in children and adults. In the United States, a rare disease is defined as a disease that affects fewer than 200,000 people in the country. There are at least 150 different disorders that are considered to be rare kidney diseases. This means that only a few thousand people in the United States may have one of these diseases, so specialized care providers may be hard to find.