>1400

Education event attendees

Career Day

> 50 %

Acceptance rate to graduate programs

Mentorship for Prospective Students in Genetic Counseling

Interns 2013-2023

49

Summer interns

Internship Program in Genetic Counseling and Bioinformatics

Applying to Genetic Counseling Graduate Programs
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Genetics Cluster Initiative

Genetics transcends departments, colleges and disciplines and generates both needs and services in the basic sciences, health care, bioethics, law, bioinformatics and communications.

Recent Publications

Spatial differences in gene expression across the dorsal raphe nucleus in a model of early Alzheimer's disease

Monday, November 25, 2024
Louis J Kolling
CONCLUSIONS: Map2k3os may serve regulatory roles relevant for tau phosphorylation and warrants further investigation to characterize its interactions. Overall, this report demonstrates the power of large-scale spatial transcriptomics technologies, while underscoring the need for convergent-data validation to overcome their limitations.

FABP4-mediated lipid accumulation and lipolysis in tumor-associated macrophages promote breast cancer metastasis

Friday, November 8, 2024
Matthew Yorek
A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote tumor growth and metastasis in various models. However, the specific molecular mechanisms that drive lipid accumulation and tumor progression in TAMs remain largely unknown. Herein, we demonstrated that unsaturated fatty acids (FAs), unlike saturated ones, are more likely to form lipid droplets in...

Effects of 28-day nose-only inhalation of PCB52 (2,2',5,5'-Tetrachlorobiphenyl) on the brain transcriptome

Sunday, October 6, 2024
Amanda J Bullert
A semi-volatile polychlorinated biphenyl (PCB) congener, PCB52, is present in the indoor air of schools; however, the effects of inhaled PCB52 on the brain have not been investigated. This study exposed male Sprague-Dawley rats at 39 days of age and female rats at 42 days of age to PCB52 for 4 hours per day over 28 consecutive days through nose-only inhalation. Neurobehavioral tests were conducted during the last 5 days of exposure. The total estimated PCB52 exposures after 28 days were 1080±20...

Upregulation of fatty acid synthesis genes in the livers of adolescent female rats caused by inhalation exposure to PCB52 (2,2',5,5'-Tetrachlorobiphenyl)

Saturday, July 27, 2024
Brynn Kyleakin Helm-Kwasny
Elevated airborne PCB levels in older schools are concerning due to their health impacts, including cancer, metabolic dysfunction-associated steatotic liver disease (MASLD), cardiovascular issues, neurodevelopmental diseases, and diabetes. During a four-week inhalation exposure to PCB52, an air pollutant commonly found in school environments, adolescent rats exhibited notable presence of PCB52 and its hydroxylated forms in their livers, alongside changes in gene expression. Female rats exhibited...

Development of a humanized anti-FABP4 monoclonal antibody for potential treatment of breast cancer

Thursday, July 25, 2024
Jiaqing Hao
CONCLUSIONS: Our current evidence suggests that targeting FABP4 with humanized monoclonal antibodies may represent a novel strategy for the treatment of breast cancer and possibly other obesity- associated diseases.

Events

Molecular Physiology and Biophysics Workshop, Weijie Du promotional image

Molecular Physiology and Biophysics Workshop, Weijie Du

Thursday, December 12, 2024 9:30am to 10:00am
Bowen Science Building
Weijie Du is a graduate student in Dr. Michael Welsh's laboratory in the Department of Molecular Physiology and Biophysics and will be presenting a workshop titled, "Hypoxia slows ciliary beating in human airway epithelia."

REDCap Surveys Training

Thursday, December 12, 2024 10:00am
Virtual
This is the third step in the REDCap training series. In this training, we will cover survey configuration and distribution such as: • Allowing potential participants to self-initiate participation in your study with public surveys • Manually and automatically sending surveys • Administering electronic consent (e-consent) forms • Controlling survey access with conditional logic and survey login • And more This training is a demo and not hands-on. After this training you will have a basic...
Hardin Open Workshops: EMBASE (Zoom) promotional image

Hardin Open Workshops: EMBASE (Zoom)

Thursday, December 12, 2024 10:00am to 11:00am
Virtual
EMBASE is a biomedical and pharmaceutical database containing bibliographic records with abstracts. Although there is overlap with records from PubMed, there are also many unique records. This hands-on session will show you how to conduct basic searches using EMBASE’s quick search box, how to conduct searches using EMTREE subject headings, and how to use subheadings for drug and disease topics. PLEASE NOTE Class will be taught via Zoom. Advance registration is required. Registrants will be...