>1400

Education event attendees

Career Day

> 50 %

Acceptance rate to graduate programs

Mentorship for Prospective Students in Genetic Counseling

Interns 2013-2023

49

Summer interns

Internship Program in Genetic Counseling and Bioinformatics

Applying to Genetic Counseling Graduate Programs
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Genetics Cluster Initiative

Genetics transcends departments, colleges and disciplines and generates both needs and services in the basic sciences, health care, bioethics, law, bioinformatics and communications.

Recent Publications

Ceramide-induced FGF13 impairs systemic metabolic health

Tuesday, April 1, 2025
Jamal Naderi
Ceramide accumulation impairs adipocytes' ability to efficiently store and utilize nutrients, leading to energy and glucose homeostasis deterioration. Using a comparative transcriptomic screen, we identified the non-canonical, non-secreted fibroblast growth factor FGF13 as a ceramide-regulated factor that impairs adipocyte function. Obesity robustly induces FGF13 expression in adipose tissue in mice and humans and is positively associated with glycemic indices of type 2 diabetes. Pharmacological...

Transcriptional repressor Capicua is a gatekeeper of cell-intrinsic interferon responses

Tuesday, March 25, 2025
Senthamizharasi Manivasagam
Early detection of viral infection and rapid activation of host antiviral defenses through transcriptional upregulation of interferons (IFNs) and IFN-stimulated genes (ISGs) are critical for controlling infection. However, aberrant production of IFN in the absence of viral infection leads to auto-inflammation and can be detrimental to the host. Here, we show that the DNA-binding transcriptional repressor complex composed of Capicua (CIC) and Ataxin-1 like (ATXN1L) binds to an 8-nucleotide motif...

CF airway epithelia display exaggerated host defense responses and prolonged cilia loss during RSV infection

Sunday, February 16, 2025
Jennifer A Bartlett
CONCLUSIONS: These findings further our understanding of innate immune dysfunction in the CF airway epithelium and suggest that virus-induced cilia injury may further compromise host defenses in CF airways.

Profiles of Exosomal microRNAs in Joint Cells and Candidate microRNAs for Cartilage Regeneration

Thursday, February 13, 2025
Venkateswaran Ganesh
The activation of chondrogenic progenitor cells (CPCs) in articular cartilage during a traumatic injury is vital for cartilage regeneration. Although our understanding of the mechanisms underlying CPC chondrogenic activation remains incomplete, there is evidence that exosomal microRNAs (miRNAs or miRs) are involved in tissue healing due to their regulating role of posttranscriptional gene expressions. In this study, we profiled enriched and differential expression of miRNAs in exosomes derived...

The oxygen level in air directs airway epithelial cell differentiation by controlling mitochondrial citrate export

Friday, January 24, 2025
Bo Ram Kim
Oxygen controls most metazoan metabolism, yet in mammals, tissue O(2) levels vary widely. While extensive research has explored cellular responses to hypoxia, understanding how cells respond to physiologically high O(2) levels remains uncertain. To address this problem, we investigated respiratory epithelia as their contact with air exposes them to some of the highest O(2) levels in the body. We asked how the O(2) level in air controls differentiation of airway basal stem cells into the ciliated...

Events

Women In Micro & Immuno Coffee Hour

Monday, January 13, 11:00am to Monday, December 8, 2025 12:00pm
Carver Biomedical Research Building
Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion! This is open to ALL — students, staff, postdocs, and faculty interested in promoting women in science. Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.

Women In Micro & Immuno Coffee Hour

Monday, March 10, 2025 11:00am to Monday, February 2, 2026 11:00am
Carver Biomedical Research Building
Join us for the Women in Micro & Immuno Coffee Hour. It is the monthly coffee hour on the second Monday of the month from 11 a.m. to noon in 1289 CBRB. Enjoy coffee, pastries and contribute to the discussion! This is open to ALL — students, staff, postdocs, and faculty interested in promoting women in science. Speakers change monthly. Contact: jessica-tucker@uiowa.edu for details.
2025 Celebration of Excellence and Achievement Among Women promotional image

2025 Celebration of Excellence and Achievement Among Women

Wednesday, April 2, 2025 3:30pm to 5:00pm
Join us for our awards ceremony and reception, honoring the giants who blazed the trail before us celebrating the incredible accomplishments crafted over the past year! Refreshments and social time will begin at 3:30 p.m., and the award celebration will begin at 4 p.m.  This event is free and open to the public. This event recognizes the recipients for the following awards: May Brodbeck Distinguished Achievement Award for Faculty Susan C. Buckley Distinguished Achievement Award for Staff...